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严重脓毒症及感染性休克时是否需用皮质醇 被引量：2

Is cortisol necessary for severe sepsis or septic shock?
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摘要 严重脓毒症及感染性休克仍是严重威胁人类健康的主要病种 ,疗效肯定的措施仅是清除感染灶。近年就是否应用糖皮质激素重又引起关注。结合文献 。
作者 王永清 樊寻梅
机构地区 首都医科大学附属北京儿童医院
出处 《国外医学（儿科学分册）》 2004年第5期243-246,共4页 Foreign Medical Sciences（Section of Pediatrics)
关键词 脓毒症 休克 感染性 皮质醇
分类号 R631 [医药卫生—外科学]
  • 相关文献

参考文献18

  • 1Carlet J.Clinical expert round table discussion(session 4) at the Margaux Conference on Critical Illness:Sepsis:Inflammation disorder,coagulation disorder,or both? A challenge for clinicians[J].Crit Care Med,2001,29(7 Suppl):S107-S108.
  • 2Keh D,Boehnke T,Weber-Cartens S,et al.Immunologic and hemodynamic effects of ""low-dose"" hydrocortisone in septic shock.A double-blind,randomized,placebo-controlled,crossover study[J].Am J Respir Crit Care Med,2003,167(4):512-520.
  • 3Oppert M,Reinicke A,Graf KJ,et al.Plasma cortisol levels before and during ""low-dose"" hydrocortisone therapy and their relationship to hemodynamic improvement in patients with septic shock[J].Intensive Care Med,2000,26(12):1747-1755.
  • 4Briegel J,Jochum M,Gippner-Steppert C,et al,Immunomodulation in septic shock:Hydrocortisone differentially regulates cytokine response[J].J Am Soc Nephrol,2001,12(Supp1 17):S70-S74.
  • 5Briegel J,Kellermann W,Forst H,et al.Low-dose hydrocortisone infusion attenuates the systemic inflammatory response syndrome.The Phospholipase A2 Study Group[J].Clin Investig,1994,72(10):782-787.
  • 6Kenyon N.Defining adrenal insufficiency in septic shock[J].Crit Care Med,2003,31(1):321-323.
  • 7Duggan M,Browen I,Flynn C.Adrenal failure in the critically ill[J].Br J Anaesth,1998,81(2):468-470.
  • 8Loisa P,Rinne T,Kaukinen S,Adrenal function and multiple organ failure in severe sepsis[J].Acta Anaesthesiol Scand,2002,46(2):145-151.
  • 9Beishuizen A,Thjis LG,Vermes I.Patterns of corticosteroid-binding globulin and the free cortisol index during septic shock and multitrauma[J].Intensive Care Med,2001,27(10):1584-1591.
  • 10Chadda K,Annane D.The use of corticosteroids in severe sepsis and acute respiratory distress syndrome[J].Ann Med,2002,34(7-8):582-589.

同被引文献19

  • 1连惠红,朱绿绮,饶小平,朱友荣,徐南平.儿童多器官功能障碍综合征150例分析[J].中华儿科杂志,2005,43(1):66-68. 被引量：6
  • 2张育才,张宇鸣,徐梁,汤定华.源于胃肠道感染的小儿脓毒性休克及多器官功能障碍综合征[J].中华急诊医学杂志,2006,15(6):494-497. 被引量：15
  • 3中华急诊医学会儿科学会急救学组.第4届全国小儿急救医学研讨会纪要[J].中华儿科杂志,1995,33:371-371.
  • 4Bivers E, Nguyen B, Havastand S, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock [ J ]. N Engl J Ned,2001, 345 (19): 1368- 1377.
  • 5Tantalean JA, Leon RJ, Santos AA, et al. Multiple organ dysfunction syndrome in children [J]. Pediatr Crit Care Med, 2003, 4(2):181-185.
  • 6Ceneviva G, Paschall JA, Maffei F, et al. Hemodynamic support in fluid-refractory pediatric septic shock [J]. Pediatrics, 1998, 101(2) : 102-119.
  • 7Carcillo JA, Fields AI. Clinical practice parameters for hemodynamic support of pediatric and neonatal patients in septic shock [J]. Crit Care Med, 2002, 30 (6): 1365-1378.
  • 8Cronin L, Cook DJ, Carlet J, et al. Corticosteroid treatment for sepsis: a critical appraisal and meta-analysis of the literature [J].Crit Care Med, 1995, 23 (8): 1430-1439.
  • 9Ballaert PE, Charpentier C, Levy B, et al. Reversal of late septic shock with suppraphysiologic doses of hydrocortisone [J].Crit Care Med, 1998,26 (4): 645-650.
  • 10Annane D, Sebille V, Troche G, et al. A 3-level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotrophin [J]. JAMA, 2000, 283(8):1038-1045.

引证文献2

二级引证文献16

国外医学（儿科学分册）
2004年 第5期

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