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HPLC法测定抗真菌药伏立康唑的有关物质 被引量：3

Determination of related substances in voriconazole by HPLC
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摘要 用HPLC法测定伏立康唑中有关物质和降解产物,与主药有很好的分离效果.色谱柱Luna C18,流动相为 30％B(→30min)70％B(A:水,B:乙腈),检测波长256nm. An RP-HPLC method for the determination of related substances and decomposition products in voriconazole was established. A Luna C18 column was used with the mobile phase of 30%B (→30min)70%B (A : water, B : acetonitnle) at the detection wavelength of 256nm.
作者 王晓玲
机构地区 西南民族大学化学与环境工程学院
出处 《西南民族大学学报（自然科学版）》 CAS 2004年第5期595-597,共3页 Journal of Southwest Minzu University(Natural Science Edition)
关键词 伏立康唑 高效液相色谱法 有关物质 降解产物 测定 voriconazole HPLC related substance decomposition product determination
分类号 O657.72 [理学—分析化学]
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参考文献3

  • 1Sofia Perea, Gennethel J. Comparison of High-Performance Liquid Chromatographic and Microbiological Methods for Determination of voriconazole Levels in Plasma[J]. Antimicrobial Agents and Chemotherapy, 2000, 44(5): 1209-1213.
  • 2宋晓静,许冰.耐药念珠菌的研究进展[J].临床皮肤科杂志,2002,31(11):732-734. 被引量：3
  • 3丁鼎乐.美国上市新药销售额锐减[J].上海医药,2003,24(8):358-358.

二级参考文献20

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二级引证文献18

西南民族大学学报（自然科学版）
2004年 第5期

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