新磺酰脲类化合物的合成及除草活性

Synthesis and Herbicidal Activity of Sulfonylurea Derivatives

将烷氧基和氟原子引入嘧啶环上取代基的碳链中,合成了12种新型单取代嘧啶环的磺酰脲化合物,其结构经1HNMR谱及元素分析确证。油菜根长法测定IC50,并进行盆栽除草活性测试。结果表明,嘧啶环上烷氧基中的氢原子被烷基、烷氧基及氟原子等基团取代后,磺酰脲分子的除草活性降低。

Alkoxy group and fluorine atom were introduced onto the carbon chain of the substituent of the pyrimidine ring, and 12 novel sulfonylurea compounds with mono substituent in the pyrimidine ring were synthesized. The structures of all compounds were confirmed by 1 H NMR and elemental analysis. Herbicidal activity tests including IC 50 in rape root and pot experiments were carried out. The results show that the herbicidal activity decreases as the hydrogen atoms of the alkoxy group at 4 position of the pyrimidine ring are substituted by alkyl, alkoxy groups or fluorine atoms.