摘要
Dihydroxy toluene was synthesized from resorcinol in 4 steps:alkylation, methylacylation, Huang Ming Long reaction and dealkylation. In first two steps ethylene dichloride was used as the solvent. This made the two reactions easy and the yields high, and also decreased the amount of DMF used in second step. The third step was a modified Huang Ming Long reaction carried out at more mild condition. The total yield of the title compound was 62%.
Dihydroxy toluene was synthesized from resorcinol in 4 steps:alkylation, methylacylation, Huang Ming Long reaction and dealkylation. In first two steps ethylene dichloride was used as the solvent. This made the two reactions easy and the yields high, and also decreased the amount of DMF used in second step. The third step was a modified Huang Ming Long reaction carried out at more mild condition. The total yield of the title compound was 62%.
出处
《应用化学》
CAS
CSCD
北大核心
2004年第10期1075-1077,共3页
Chinese Journal of Applied Chemistry
基金
陕西省教育厅资助项目(03JC01)
关键词
二羟基甲苯
间苯二酚
二氯乙烷
烷基化
甲酰化
黄鸣龙反应
转移烷基化
dihydroxy toluene,resorcinol,ethylene dichloride,alkylation,methylacylate,Huang Ming-Long reaction ,dealkylation
