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邻甲苯基苯甲腈的合成及其在心血管药物中的应用与前景 被引量:2

Synthesis and application in heart-vein-remedy of O-tolylbenzonitrile
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摘要 介绍了邻甲苯基苯甲腈的合成方法及其在新型血管紧张素Ⅱ拮抗体药物中的应用,以邻甲苯基苯甲腈为基础中间体开发的几种产品的合成,邻甲苯基苯甲腈的发展前景。 Synthesis routes and application in angiotensin II receptor antagonists harmaceuticals of O-tolylbenzonitrile are reviewed, some products derived from O-tolylbenzonitrile are also introduced, at the same time ,the development prospect of O-tolylbenzonitrile is viewed.
作者 付春
出处 《化工中间体(科技.产业版)》 2004年第3期17-19,27,共4页
关键词 邻甲苯基苯甲腈 合成 心血管药物 应用 催化一步合成法 闭环法 保护基多步法 O-tolylbenzonitrile, angjotensin II receptor antagonists pharmaceuticals, Synthesis, application
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