不同方法处理的同种异体骨移植红细胞免疫功能的变化

The Change of Red Cell Immunological Function in the Transplantation of Homogenous Bone Grafts Preserved by Different Methods

本文道报27例同种异体骨移植兔的红细胞免疫功能指标检测结果。红细胞C_3b受体花环率变化,以异体骨花环率最高,液氮骨其次,AAA骨花环率形成率则在正常对照值范围内变化。结果提示异体骨移植能引起明显的免疫反应,液氮骨可有一定的抗原性,能引起免疫反应,冻干骨免疫反应较低下,而AAA骨则不引起免疫反应。本文对同种异体骨移植后的红细胞免疫功能变化的机理与临床意义进行了讨论。

The red cell immunolgical function parameter was determined in 27rabbits of homo genous bone grefts transplantation. The sequences of the formation rates of C3b receptor rasette of RBC, from the highest to the lowest, were allograft liquid nitrogen preserved grafts, freeze——dried grafts, and AAA bone grafts, the latter one varied within the normal limit. It is conclude that the bony allograft may cause abvious immune reaction, liquid nitrogen prserved bone has certain antigenicity and cause immune reaction. The fre- ezed——dried bone evokes little immune reaction, and AAA bone has no immune reaction. The mechanism and clinical significance of changes in the red immunological function in bony allograft are discussed.