UF-100尿沉渣分析仪鉴别血尿来源

Diagnosis of origin of hematuria with UF-100 urinary sediment analyzer

目的 探讨UF 1 0 0尿沉渣分析仪鉴别血尿来源的临床应用价值。方法 用UF 1 0 0尿沉渣分析仪对 1 5 9例肾小球性血尿和 2 1 3例非肾小球性血尿标本进行检测 ,统计红细胞各项数据 ,并将仪器红细胞提示信息与普通光学显微镜检查结果进行比较。结果 肾小球性血尿和非肾小球性血尿标本的红细胞平均前向散射强度 (RBC MFsc)分别为 5 6 .9± 1 6 .3和 1 0 1 .7± 5 .8(P <0 .0 1 )、红细胞平均前向散射光分布宽度 (RBC Fsc DW)分别为 36 .1± 1 2 .8和 1 5 .4± 6 .2 (P <0 .0 5 )、70 %红细胞前向散射光强度 (RBC P70 Fsc)分别为 5 7.8± 1 5 .8和 1 2 1 .1± 6 .2 (P <0 .0 1 ) ;红细胞提示信息与普通光学显微镜检查结果判断肾小球性血尿的敏感性分别为93.7%和 80 .5 % ,差异有显著性 (P <0 .0 1 ) ,特异性分别为 83.1 %和 87.3% ,差异无显著性 (P >0 .0 5 )。结论 UF 1 0 0尿沉渣分析仪检测方法简便、快速 ,无主观因素干扰 ,结果敏感准确、客观可靠 。

Objective To evaluate the clinical significance of urinary sediment analyzer measurement in diagnosis of the origin of hematuria. Methods Urine samples from 159 patients with glomerular disease and 213 patients with non glomerular disease were measured by UF 100 urinary sediment analyzer and microscopic morphology. Results The RBC MFsc, RBC Fsc DW and RBC P 70 Fsc of patients with glomerular disease and non glomerular disease were respectively 56.9±16.3 and 101.7±5.8( P <0.01), 36.1±12.8 and 15.4±6.2( P <0.05), 57.8±15.8 and 121.1 ±6.2 ( P <0.01). The sensitivity and speciality for UF 100 urinary sediment analyzer and microscopic morphology were 93.7% and 80.5%( P <0.01), 83.1% and 87.3% respectively. Conclusions Urine analysis by UF 100 urinary sediment analyzer is a highly sensitive, easy and reliable method to differentiate glomerular disease from non glomerular disease.