期刊文献+

Analysis of clinical effect of high-intensity focused ultrasound on liver cancer 被引量:25

Analysis of clinical effect of high-intensity focused ultrasound on liver cancer
下载PDF
导出
摘要 AIM: To evaluate the clinical effect of high-intensity focused ultrasound (HIFU) in the treatment of patients with liver cancer.METHODS: HIFU treatment was performed in 100 patients with liver cancer under general anesthesia and by a targeted ultrasound. Evaluation of efficacy was made on the basis of clinical symptoms, liver function tests, AFP,MRI or CT before and after the treatment.RESULTS: After HIFU treatment, clinical symptoms were relieved in 86.6%(71/82) of patients. The ascites disappeared in 6 patients. ALT (95±44) U/L and AST(114±58) U/L before HIFU treatment were reduced to normal in 83.3%(30/36) and 72.9%(35/48) patients,respectively, after the treatment. AFP was lowered by more than 50% in 65.3%(32/49) patients. After HIFU treatment,MRI or CT findings indicated coagulation necrosis and blood supply reduction or disappearance of tumor in the target region.CONCLUSION: HIFU can efficiently treat the patients with liver cancer. It will offer a significant noninvasive therapy for local treatment of liver tumor. AIM:To evaluate the clinical effect of high-intensity focused ultrasound(HIFU)in the treatment of patients with liver cancer. METHODS:HIFU treatment was performed in 100 patients with liver cancer under general anesthesia and by a targeted ultrasound.Evaluation of efficacy was made on the basis of clinical symptoms,liver function tests,AFP, MRI or CT before and after the treatment. RESULTS:After HIFU treatment,clinical symptoms were relieved in 86.6%(71/82)of patients.The ascites disappeared in 6 patients.ALT(95±44)U/L and AST (114±58)U/L before HIFU treatment were reduced to normal in 83.3%(30/36)and 72.9%(35/48)patients, respectively,after the treatment.AFP was lowered by more than 50% in 65.3%(32/49)patients.After HIFU treatment, MRI or CT findings indicated coagulation necrosis and blood supply reduction or disappearance of tumor in the target region. CONCLUSION:HIFU can efficiently treat the patients with liver cancer.It will offer a significant noninvasive therapy for local treatment of liver tumor.
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2004年第15期2201-2204,共4页 世界胃肠病学杂志(英文版)
  • 相关文献

参考文献4

二级参考文献36

  • 1[1]Lynn,J.G.et al;A new method for the generation and use of focused ultrasound in experimental biology.J.Gen. Physiol.26;179—193;1942.
  • 2[2]Vaughan, M.G.et al Minimally invasive cancer surgery using focused ultrasound:a pre-clinical,normal study.Br.J.Radiol. 67:267—274;1994.
  • 3[3]Warwick,R.,Trackless lesions in nervous tissues produced by high in tensity ultrasound(high frequency mechanical waves).J.Anat.102:387—405;1968.
  • 4[4]Fry, F.J.Precision high intensity focusing ultrasound machines for surgery.Am.J.Phys.Med.37:152—156;1958.
  • 5[5]Sanghvi, N.T. et al; High intensity focused ultrasound(HIFU)for the treatment of rectal tumors:A feasibility study.IEEE Ultrasonics symposium. 1895—1898,1994.
  • 6[6]Foster, R.S. et al;High intensity focused ultrasound in the treatment of prostatic disease. Eur Urol.23(suppl.1):29—33;1993.
  • 7[7]Gelet,A.; et al;High intensity focused ultrasound experimentation on human benign prostatic hypertrophy. Eur. Urol.23(suppl.1):44—47;1993.
  • 8[8]Sanghvi,N.T. et al;Ultrasound intracavity system for imaging, therapy planning and treatment of focal disease. IEEE Ultrasonics symposium. 1249—1252,1992.
  • 9[9]Vallancien,G. et al.Focused extracorporeal pyrotherapy.Eur.Urol.23(suppl.1):48—52;1993a.
  • 10[10]ter Haar, G.R. Ultrasound focal beam surgery. Ultrasound Med. Biol.21:1089—1100;1995.

共引文献122

同被引文献122

引证文献25

二级引证文献135

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部