高血压合并脑卒中患者动态血压监测参数分析

Evaluation of the various ABPM parameters relevant to stroke in hypertension

目的 对高血压合并脑卒中患者的动态血压监测 (ABPM )参数进行分析 ,以评价各参数对脑卒中发生的影响。方法 将 2 0 0 3年 2～ 11月确诊为高血压合并脑卒中的 12 1例住院患者作为脑卒中组 ,80例高血压不伴脑卒中的患者作为对照组 ,分析ABPM各参数对脑卒中发生的影响。结果 脑卒中组的收缩压 (SBP)负荷、白天和夜间SBP负荷均值及平均SBP与对照组的差异有显著性 (P <0 .0 5 ) ,余指标的差异无显著性 (P >0 .0 5 ) ;平均SBP负荷、白天和夜间SBP负荷均值及平均SBP增高易引起脑卒中 ,以平均SBP负荷影响最大。结论 平均SBP负荷、白天和夜间SBP负荷均值及平均SBP对脑卒中发生可能具有预测价值 ;有效控制血压 ,特别是SBP 。

Objective To evaluate the various ABPM parameters relevant to stroke. Methods We analyzed the ABPM recorded from 2003 Feb. to Nov. in 121 hypertension ward patients with stroke.Eighty hypertensive patients without stroke were matched as control.All ABPM parameters were analyzed and evaluated in the two groups. Results Of all the differential ABPM parameters,mean systolic load, day and night mean systolic load and mean systolic pressure were the most prominent factors between the two groups (P<0.05). The rest showed no statistical differences.The most important parameter relevant to stroke was the mean systolic load. Conclusion Mean systolic load, day and night mean systolic load and mean systolic pressure seem to be the predictive parameters of stroke therefore the adequate control of BP,especially SBP may have an impact on stroke.