糖尿病2545例血脂检测结果与临床分析

Results and clinic significance of blood Lipids in 2545 diabetic patients

目的 总结糖尿病患者血脂异常的规律 ,分析血脂异常与某些慢性并发症的关系。方法 建立计算机管理糖尿病资料库 ,血脂测定及并发症筛查。结果 2 5 4 5例糖尿病患者中 ,血脂 4项正常组 882例 ,占 35 0 % ;血脂异常16 6 3例 ,占 6 5 0 % ,其中总胆固醇 (TC)和甘油三酯 (TG)都升高者占 2 2 8%。高血压检出率正常组 39 2 % ,血脂异常组4 8 3% ,其中高TC和高TG组高达 5 3 2 %。大血管病变的检出率与血脂正常组 (2 4 0 % )比较 ,高TC高TG组为33 6 % ,P <0 0 1。肾脏病变检出率血脂正常组为 2 3 2 % ,高TC组为 2 9 3% ,P <0 0 5 ;高TC高TG组为 30 6 % ,P <0 0 1。高TC组黄斑病变检出率较高 ,为 10 2 % (P <0 0 5 )。神经病变的检出率在血脂异常各组与血脂正常组均无显著性差别。结论 本组糖尿病患者血脂异常的发生率高达 6 5 % ,血脂异常以TC和TG均升高较多。高血压的检出率与血脂异常有一定相关性 。

Objective To investigate the prevalence of lipids disorder in Chinese patients with diabetes and the relationship of lipids disorder with chronic complication. Methods 2545 diabetic patients were analyzed for their different lipids disorder based on the clinic data.Results In this group of Chinese diabetic patients, only 35% with normal lipids level and 65 0% with lipids disorder, including 22 8% with hypercholesterolemia and hypertriglyceridemia mixed. More patients with hypertension were found in these with than those without lipids disorder (48 3% vs. 39 2%, P < 0 01).Conclusion Lipids disorder is extremely common in Chinese diabetic patients, particularly hypercholesterolemia and hypertriglyceridemia mixed, and obviously related with hypertension.