支气管哮喘发作与病毒感染的关系

Relation between Bronchial Asthma Breakout and Viral Infection

目的 探讨支气管哮喘发作与病毒感染的关系。方法 62例支气管哮喘发作期患者于住院当日采集 2ml静脉血 ,采用酶联免疫吸附试验进行呼吸道病毒病原体检测。结果 呼吸道合胞病毒 (RSV)、腺病毒 (AdV)阳性率最高 ,分别为 3 0 .5 %、2 7.4%,其次为柯萨奇病毒(CVB)、EB病毒 (EBV) ,分别为 11.3 %、6.5 %,埃可病毒 (ECHOV)为 4.8%,副流感病毒 (PIV)及流感病毒B(IVB)均为 1.6%,流感病毒A(IVA )为 0 %。结论 提示腺病毒 (AdV)、呼吸道合胞病毒 (RSV)、柯萨奇病毒 (CVB)、EB病毒 (EBV)是最主要的导致哮喘急性发作的病原体。

Objective To investigate the relation between bronchial asthma breakout and viral infection.Methods 2 ml of venous blood was collected from each of 61 patients with bronchial asthma outbreak on that very day when they hospitalized. Each sample was tested for respiratory viruses with enzyme linked immunoadsorbent assay (ELISA).Results The highest positive rates were found in respiratory syncytial virus (RSV,30.5%) and adenovirus (AdV,27.4%),and the other findings were as following: Coxsackie virus (CV,11.3%), EB virus (EBV,6.5%),echovirus (ECHOV,4.8%),parainfluenza virus (PIV,1.6%), influenza virus B (IVB,1.6%) and influenza virus A (IVA,0%). Conclusion It is suggested that RSV,AdV,CV and EBV be the main pathogens,which lead to asthma outbreak.