彩色多普勒血流显像在糖尿病肾病中的应用研究

Study of Color Doppler Flow Imaging in Diabetic Nephropathy

目的 :探讨彩色多普勒血流显像 (CDFI)在糖尿病肾病诊疗中的临床应用价值。方法 :总结了 15例肾功能不全期糖尿病肾病 (DN)患者的多普勒超声检查结果 ,并与年龄匹配的 15例临床DN期和 2 0例正常对照组对比分析。结果 :肾功能不全期DN患者搏动指数 (PI)和阻力指数 (RI)高于临床DN期患者P <0 .0 1和 0 .0 5 ,收缩期峰值流速、平均流速低于临床DN期P <0 .0 5和 0 .0 1。与正常组比较 ,二期DN的PI、RI明显增高P <0 .0 1,肾功能不全期DN舒张末期流速和平均流速明显降低P均 <0 .0 1,临床DN期收缩期峰值流速增高P <0 .0 5 ,舒张末期流速降低P <0 .0 5。结论 :彩色多普勒血流显像在预测肾脏损害和判断肾功能不全方面有一定价值。

Objective To investigate the clinical value of color Doppler flow imaging in patients with diabetic nephropathy.Methods Result of Doppler ultrasound examination in 15 patients with diabetic renal failure age matched 15 cases of clinical diabetic nephropathy (DN) and 20 cases of normal controls was reported.Results The pulsative index (PI) and resistance index (RI) of the patients with diabetic renal failure were significantly higher and the systole peak velocity and mean velocity were lower than those of clinical DN.Compared with normal controls,the PI and RI in the patients with clinical DN or diabetic renal failure were greatly increased.The end-diastolic velocity of blood flow and the mean velocity were significantly reduced in the patients with diabetic renal failure. The peak velocity of blood flow during systole was increased and the end-diastolic velocity of blood flow was reduced in the patients with clinical DN.Conclusion The color Doppler flow imaging might be valuable in forecasting the renal injury and judging the renal failure.