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可溶性血管粘附蛋白、C反应蛋白在老年冠心病发病中的作用 被引量:3

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摘要 目的 :探讨可溶性血管粘附蛋白 - 1(solublevascularadhesionprotin 1,sVAP 1)、C反应蛋白 (Creactivepro tein ,CRP)在老年冠心病患者体内表达变化及其与疾病发生、发展的关系。方法 :将老年冠心病患者分为非急性心肌梗死、急性心肌梗死两组 ,通过ELISA法分别检测两组患者及健康老年人血清sVAP 1、CRP水平并对二指标作组间比较以分析各组之间差异。结果 :二指标以老年急性心肌梗死冠心病患者体内水平为最高 ,与老年非急性心肌梗死冠心病患者及健康老年人之间的差别有显著性 (P <0 0 1) ;老年非急性心肌梗死患者组二指标较正常对照组有显著升高 (P <0 0 5或P <0 0 1)。sVAP 1与CRP二指标间作相关分析 ,结果显示二组内二指标间均有相关性 ,正常对照组内两指标间无相关性。结论 :老年急性心肌梗死、老年非急性心肌梗死患者体内存在sVAP 1、CRP异常表达 ,其表达水平与疾病严重程度有关 ,sVAP 1、CRP参与心血管疾病的形成与发展。
出处 《江苏大学学报(医学版)》 CAS 2004年第4期323-325,共3页 Journal of Jiangsu University:Medicine Edition
基金 镇江市科委社会发展基金资助项目 (SH2 0 0 3 0 2 9)
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