原发性高血压患者24h平均脉压与左室肥厚的关系

Relationship between 24-hour average pulse pressure and left ventricular hypertrophy in essential hypertension

目的 :探讨 2 4 h平均脉压 (PP)与原发性高血压患者左室肥厚的关系。方法 :将 2 1 8例原发性高血压患者分为 2组 :左室肥厚组和非左室肥厚组 ,进行 2 4 h无创性动态血压监测。再以 PP≥ 60 mm Hg、脉压 <60 mm Hg分为 2个亚组。结果 :左室肥厚组与非左室肥厚组2 4 h平均脉压有显著性差异 (P<0 .0 5) ,PP≥ 60 mm Hg组左室肥厚发生率较 PP<60 mm Hg组显著增加 (P<0 .0 5) .结论 :原发性高血压患者 2 4 h平均脉压与左室肥厚密切相关 ,脉压增大是心血管病的高危因素。

Objective:To investigate the relationship between 24-hour average pulse pressure (PP) and left ventricular hypertrophy (LVH) in essential hypertension (EH).Methods:A total of 218 patients with EH were studied by Doppler echocardiography and ambulatory blood pressure monitoring. They were divided into groups with or without LVH, and high PP (PP≥60mm Hg) and low PP (PP<60mm Hg) groups, respectively.Results:24-hour average PP was higher in patients with LVH than that without LVH (P<0.05). LVH were more common in high PP group than in low PP group (P<0.05). Conclusion:24-hour average PP is related to LVH occurrence in patients with EH. The increase of PP is a risk factor for cardiovascular diseases.