莫西沙星与左氧氟沙星治疗下呼吸道感染疗效对比研究

Comparitive Study on Moxifloxacin vs Levofloxacin in Treatment of Lower Respiratory Tract Infection

目的 :评价用莫西沙星与左氧氟沙星治疗下呼吸道感染的临床疗效及安全性。方法 :将 5 4例下呼吸道感染患者随机分成治疗组 2 6例和对照组 2 8例 ,分别给予莫西沙星和左氧氟沙星治疗。结果 :研究结果显示治疗结束后第 7d ,莫西沙星组和左氧氟沙星组的临床有效率分别为 6 0 %和 6 3.16 % ,莫西沙星 2 6例中 5例 (19.2 3% )出现不良反应 ,而左氧氟沙星 2 8例中为 7例 (2 5 % )。结论 :莫西沙星对治疗下呼吸道感染的临床疗效确切。

Objective: To evaluate the efficacy and safety of moxifloxacin vs levofloxacin in the treatment of lower respiratory tract infection. Method: 26 cases patients with patients with lower respiratory tract infection were enrolled as treated group which was treated with moxifloxacin and other 28 cases were enrolled as controlled group treated with levofloxacin.Result: The research result indicated that the total clinical effective rates on the first day after the end of treatment period in the treated groups were 60% and 63.16% , respectively Side effect happened in moxifloxacin group had six cases ( 19.23% ), seven cases in levofloxacin group(25%).Conclusion: The efficacy and safety of moxifloxacin injection were good and reliable.