颌骨嗜酸性粒细胞肉芽肿21例临床分析

Eosinophilic granuloma of the jaw: An analysis of 21 cases

目的:总结分析颌骨嗜酸性粒细胞肉芽肿的诊治经验。方法:回顾分析1983-2002年间21例颌骨嗜酸性粒细胞肉芽肿的病例资料,对研究对象的性别、年龄、病变部位、临床表现、治疗等进行总结分析。结果:男女之比为13:8,以儿童及青少年多见,2-10岁占76％,中位年龄为8岁。下颌骨多见,18例,上颌骨1例,上、下颌骨同时发生2例。结论:颌骨嗜酸性粒细胞肉芽肿临床上少见,病理诊断较为明确。治疗需要采取局部手术刮治,预后较好。

PURPOSE: To study the clinical features and treatment of eosinophilic granuloma of the jaw (EGJ) in 21 cases. METHODS: 21 patients with EGJ treated from 1983 to 2002 were reviewed, including the sexes, ages, extent of lesions, clinical features and treatment methods. RESULTS: The male to female rate was 13:8. 76% of the cases were a-mong 2-10 years. The median age was 8 years.18 lesions were in the mandible, 1 was in the maxilla and 2 involved the mandible and maxilla. CONCLUSIONS: EGJ was rarely seen clinically, lack of specificity. Pathology can confirm the diagnosis. Surgery is still the major treatment modality. Combination of radiotherapy or chemotherapy maybe valuable. The prognosis of the patients was generally good.