间质性肌炎的临床和病理特征

The Clinical and Pathological Characteristics of Interstitial Myositis

目的 总结间质性肌炎 ( interstitial myositis,IM)临床特点及病理特征 ,探讨 IM的诊断、治疗效果和预后。方法 综合分析作者医院 2 3例 IM的临床资料 ,并与 93例多发性肌炎、3 4例皮肌炎进行比较。结果 IM临床表现以肌无力、肌肉疼痛、血清酶谱增高、肌电图及病理学异常为特征 ,治疗以激素为主。结论 病理学检查对 IM诊断及疗效判断有重要价值。

Objective To evaluate the clinical and pathological characteristics of interstitial myositis for its role to therapeutics and prognosis. Methods To study the clinical datum of 23 cases of interstitial myositis were reviewed retrospectively. 93 cases polymyositis and 34 cases dermatomyositiswereservedas controls. Results The clinical situations of interstitial myositis are characterized by the amyosthenia,the myodynia,the increase of value of muscular enzyme in serum and the abnormality of the electromyogram and the pathology. Corticosteriods are proved to be the principal therapeutic drugs. Conclusions Pathological examination plays a crucial role in the diagnosis of the interstitial myositis and the judgement of effect of drugs in question.