补肾中药治疗绝经后骨质疏松症疗效分析

Clinical effect of kidney-tonifiying herbs on postmenopausal Osteoporosis

目的：客观评价补肾中药治疗绝经后骨质疏松症治疗作用。方法：绝经后骨质疏松症患者７７例随机分成两组，分别应用补肾中药、密钙息治疗半年。结果：补肾中药、密钙息治疗半年后，骨质疏松症腰背症状明显缓解（Ｐ＜０．５），腰椎骨质密度平均值升高（Ｐ＜０．０５）；尺、桡骨矿物质含量较治疗前明显增加（Ｐ＜０．０５）；两组间无明显差异（Ｐ＞０．０５）。两组治疗后Ｕ－Ｃａ／Ｃｒ、Ｕ－ＨｏＰ／Ｃｒ的测定值均明显下降（Ｐ＜０．０５），但补肾组ＡＫＰ测定值明显上升（Ｐ＜０．０５），密钙息组ＡＫＰ测定值明显下降（Ｐ＜０．０５），ＡＫＰ测定值两组间有明显差异（Ｐ＜０．０５）。结论；补肾中药与密钙息均能较好地治疗绝经后骨质疏松症。提示：补肾中药有促进骨形成的作用，还有成本低、副作用少等优点。

AIM To evaluate the efficacy of some traditional Chinese kidney-invigorating hearbs-for treating postmenopausal osteoporosis. METHODS 77 cases of postmenopausal osteoporosis,were divided into two groups (treated with kidney-invigorating herb and miacalcic, respectively. RESULTS 6 months after treatment with kidney-invigorating herb and miacalcic,the symtoms of patients were improved (P<0. 05). The bone density of lumbar vertebra was significantly higher than that before treatment (P<0. 05). The ulnar and radial bone mineral content was higher than that before treatment (P<0. 05). There was no significant difference between the two groups (P>0. 05 ). In the two groups, the ratio of fasting urinary calcium and hydroxyproline to creatinin was lower than that before treatment (P< 0. 05). The concentration of serum alkaline phosphatase of the group treated with kidney-invigorating herb increased (P<0. 05)while that in the group treated with miacalcic decreased (P<0. 05),the diffearence being significant(P<0. 05). CONCLUSION Kidney-tonifying herbs and miacalcic could improve postmentopausal osteoporotic symptoms equally. The kidney-tonifying herbs had action of promoting bone for and advantages of low prices and low side effect.