老年人脑梗死与胆红素和血管性血友病因子的相关性

Correlation between bilirubin,Von willbrand's Factor and cerebral infarction in aged patients

目的 探讨老年人脑梗死与血清胆红素和血管性血友病因子 (vWF)的关系。方法 选择老年人脑梗死组 (4 2例 )和对照组 (19例 ) ,测定血清总胆红素 (TBIL)、直接胆红素 (DBIL)、间接胆红素 (IBIL)、低密度脂蛋白胆固醇 (LDL)和血浆vWF的浓度 ,分析其与老年人脑梗死之间的关系。结果 老年人脑梗死TBIL、DBIL、IBIL明显降低 ,LDL、vWF显著升高 ,与对照组比较差异有显著意义。结论 胆红素和血管性血友病因子的异常变化与老年人脑梗死的发生、发展密切相关。

Objective To explore the relationship between cerebral infarction and serum bilirubin or Von willbrand's Factor in aged patients.Methods To determine the serum concentration of total bilirubin(TBIL),direct bilirubin(DBIL),indirect bilirubin(IBIL),low density lipoprotein cholesterol(LDL) and plasma vWF of aged cerebral infarction group(n=42) and control group(n=19),and then analyse its relationship with cerebral infarction in aged patients.Results Compared with control group,the levels of TBIL,DBIL and IBIL in aged patients with cerebral infarction were obviously decreased,while the levels of LDL and vWF were highly increased,the difference had statistics significance.Conclusion Changes of serum bilirubin or Von willbrand's Factor closely correlation with the cerebral infarction in aged patients.