头孢曲松钠在胃肠道外科围手术期的合理应用

Clinical study of ceftriaxone used in periorpertive stage of gastrointestinal surgery

目的 观察在胃肠手术围手术期应用抗生素方法不同所达到的预防感染的效果。方法 回顾性分析 2 0 0 0年 1月至 2 0 0 4年 1月各种胃肠手术患者按抗生素使用分为三组 :A组单用头孢曲松钠共 4 76例 ;B组头孢曲松钠合并其他类型抗生素共 392例 ;C组其他类型抗生素单用或合用共 5 86例。结果 三组感染发生率分别是A组 1 2 6 %、B组 1 2 7%、C组 1 5 3% ,三组间感染发生率差异无显著意义。结论 胃肠道围手术期长期或联合应用抗生素并不能进一步降低感染发生率。

Objective To observe the effect of different kinds of antibiotics used in periopertive stage of gastrointestinal surgery.Methods Three groups were divided according to antibiotics used.Group A:476 cases used ceftriaxone only,group B:392 cases used ceftriaxone plus another kinds of antibiotics,group C:586 cases used any other kinds of antibiotics not including ceftriaxone.Results There were no significant difference in the rate of infection in perioperative stage of gastrointestinal surgery among three groups.Conclusion The rate of infection of gastrointestinal surgery in perioperative stage cann't be decreased by prolonging antibiotics use or using too many kinds of antibiotics.