10%丙草醚水悬浮剂的研制

Study on the Formulation Preparation of 10% ZJ0273 Suspension Concentrate

就10%丙草醚水悬浮剂的配方进行了研究。采用湿式超微粉碎法加工工艺,对该制剂中润湿分散剂、防冻剂、消泡剂及制剂pH值等进行了筛选试验,确定了优惠配方。实验制剂经低温和热稳定性试验,外观无明显分层,水中分散性良好,悬浮率>95.0%,有效成分分解率<3.0%,各项指标均符合水悬浮剂要求。

The formulation of 10% ZJ0273 suspension concentrate was developed with the method of wetmilling after optimizing the receipt with main adjuvants, such as, wetting-dispersing agents, anti-freeze agents,as well as pH values of the formation. Results showed that its physical and chemical properties were not changedsignificantly after the formulation stored under cold and thawing conditions respectively. And its flowable ratewas higher than 95.0%, the decomposed rate of the active ingredient was less than 3.0%.