地塞米松减轻曲马多术后镇痛时恶心呕吐的临床观察

Antiemetic Effect of Dexamethasone for Postoperative Patients Undergoing Control Epidural Analgesia with Tramado

目的 :探讨地塞米松减轻曲马多术后镇痛时恶心呕吐的临床效果。方法 :选择术后自愿硬膜外镇痛(PCEA)的病例 6 0例 ,随机分为试验组 (地塞米松 +曲马多 +0 .15 %布比卡因 )和对照组 (格拉司琼 +曲马多 +0 .15 %布比卡因 )。结果 :两组病人术后疼痛评分 (VAS法 ) ,镇静评分及恶心呕吐的发生率无明显差异 (P >0 .0 5 )。结论 :地塞米松可以减轻曲马多术后镇痛时恶心呕吐的发生 ,效果良好 ,不增加副作用 。

Objectve:To evaluate the antiemetic effect of dexamethasone for postoperative patients undergoing control epidural analgesia with tramadol.Methods: Sixty patients accepting the operations under epidural anesthesia were randomly assigned to two groups. The patients received dexamethasone and tramadol and 0.15% bupivacaine (experimental group) or granisetron and tramadol and 0.15% bupivacaine (controlled group). The occurrence of postoperative nausea and vomiting (PONV) was observed in 24 hours postoperatively. Results: There was no significant difference for the incidence rate of PONV between the two groups. Conclusion: Dexamethasone can significantly reduce PONV.