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脂联素的研究进展 被引量：17

Research progress on adiponectin
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摘要 本文综述了脂联素的结构、生理功能、影响因素 ,以及与脂联素功能失调相关的疾病。 This article reviews the structure, function and impact factor of adiponectin and summarizes some diseases that relates to the disfunction of adiponectin.
作者 黄宇虹 高秀梅 张伯礼
机构地区 天津中医学院中医药研究中心
出处 《中国临床药理学与治疗学》 CAS CSCD 2004年第9期961-965,共5页 Chinese Journal of Clinical Pharmacology and Therapeutics
关键词 脂联素 糖尿病 代谢综合征 心血管疾病 adiponectin diabetes mellitus metabolic syndrome cardiovascular disease
分类号 R966 [医药卫生—药理学]
  • 相关文献

参考文献30

  • 1[1]Scheen AJ. Pathophysiology of type 2 diabetes [ J]. Acta Clin Belg, 2003; 58(6): 335-41
  • 2[2]Takahashi M, Arita Y, Yamagata K. Genomic structure and mutations in adipose-specific gene, adiponectin[J]. Int J Obse, 2000; 24: 861- 8
  • 3[3]Saito K, Tobe T, Minoshima. Organization of the gene for gelatin-binding protein(GBP28) [J]. Gene, 1999; 229( 1 - 2): 67- 73
  • 4[4]Hare K, Boutin P, Mori Y. Genetic variation in the gene encoding adiponectin is associated risk of type 2 diabetes in the Japanese population[J]. Diabetes, 2002; 51(4): 1294
  • 5[5]Ohashi K, Ouchi N, Kihara S, Funahashi T, Nakamura T,Sumitsuji S, et al. Adiponectin I164T mutation is associated with the metabolic syndrome and coronary artery disease[J]. J Am Coll Cardiol, 2004; 43(7): 1195-200
  • 6[6]Vasseur F, Helbecque N, Dina C. Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipoctye-secreted adiponectin hormone levels and contributes to the genetic risk for type 2 diabetes in French Caucasians[J]. Hum Mol Genet, 2002; 11(21):2607 - 14
  • 7[7]Qi Y, Takahashi N, Hileman SM, Patel HR, Berg AH, Pajvani UB, et al. Adiponectin acts in the brain to decrease body weight[J]. Nat Med, 2004; 10(5): 524- 9
  • 8[8]Furukawa K, Hori M, Ouchi N, Kihara S, Funahashi T, Matsuzawa Y, et al. Adiponectin down-regulates acylcoenzyme A:cholesterol acyltransferase-1 in cultured human monocyte-derived macrophages[J]. Biochem Biophys Res Commun, 2004; 317(3): 831 - 6
  • 9[9]Maruyoshi H, Kojima S, Funahashi T, Miyamoto S, Hokamaki J, Soejima H, et al. Adiponectin is inversely related to plasminogen activator inhibitor type 1 in patients with stable exertional angina[J]. Thromb Haemost, 2004; 91(5): 1026-30
  • 10[10]Komatsu M, Ohfusa H, Sato Y, Yajima H, Yamauchi K,Aizawa T, et al. Strong inverse correlation between serum adiponectin level and heart rate-corrected QT interval in an apparently healthy population: A suggestion for a direct antiatherogenic effect of adiponectin[J]. Diabetes Care, 2004; 27(5):1237 - 8

同被引文献259

引证文献17

二级引证文献55

中国临床药理学与治疗学
2004年 第9期

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