摘要
对145只自然感染胃肠线虫的山羊进行了国产表阿佛菌素驱除胃肠线虫的临床疗效试验。单次给药治疗21d后,其0.1、0.2、0.4mg/kg组的精计驱虫率均为100%,驱净率分别为100%、100%和90%～100%,粗计驱虫率分别为100%、100%和99.4%～100%,均显著优于阳性对照组(0.15%、0和0)和对照药物盐酸左旋咪唑组(38.4%、35%～85%和66.5%～85.9%)(P<0.05或P<0.01),表明表阿佛菌素具有明显的驱除胃肠线虫作用,其临床推荐剂量为0.2mg/kg。
The clinical efficacy of eprinomectin against gastrointestinal nematode infections was observed in 145 goats. The accurate helminthic rates at 21 days after treatment once with subcutaneous injection at 0.1,0.2 or (0.4 mg/kg) bw are all 100% against gastrointestinal nematodes. The rude helminthic rates are 100%、100% or (99.4%)～100% respectively. The helminthic depurative rates are 100%, 100% or 90%～100% respectively. They were remarkably higher than the rates of the control (non-treatment) group(0.15%、0 and 0) and the (control) drug group(38.4%、35%～85% and 66.5%～85.9%), respectively(P<0.01 or P<0.05). The results showed that the efficacy of eprinomectin against gastrointestinal nematode infections is remarkable. The (recommended) dosage is 0.2 mg/kg bw.
出处
《中国兽药杂志》
2004年第9期41-44,共4页
Chinese Journal of Veterinary Drug
关键词
表阿佛菌素
胃肠道
线虫
山羊
自然感染
eprinomectin
gastrointestinal nematodes
natural infection
efficacy
the recommended dosage
