心肺危险指数与肺癌术后并发症的预测

Cardiopulmonary risk index and prediction of postoperative complications after lung cancer surgery

目的研究心肺危险指数与肺癌术后并发症的关系.方法对1 144例接受肿瘤切除手术的肺癌患者进行分析,从临床资料中计算出心脏危险指数(CRI)和肺危险指数(PRI),两者相加之和为心肺危险指数(CPRI),分析CPRI与肺癌术后并发症的关系.结果术后30天内发生并发症的有167例(14.6%),死亡25例(2.2%).本组CPRI分为1～10级,其中CPRI＜4的有808例,≥4的有336例.以CPRI≥4为标准,其预测肺癌手术风险的敏感性、特异性分别为81.4%、79.5%.结论CPRI可以作为预测肺癌术后并发症的一项重要指标,但不能完全预计肺切除术后风险,仍需结合其它因素综合考虑.

Objective To elucidate the relationship between cardiopulmonary risk index and post-operative complications after lung cancer surgery. Methods 1144 lung cancer patients who underwent surgery were studied and their cardiac risk index (CRI) , pulmonary risk index (PRI) and cardiopulmonary risk index (CPRI) were calculated from the preoperative clinical data. The value of CPRI in predicting postoperative complications was estimated. Results Postoperative complications were observed in 167 patients (14. 6%) and 25 (2. 2%)died of complications. CPRI scores ranged from 1 to 10. There were 808 patients with CPRI<4 and 336 with CPRI≥4. Using CPRI≥4 as the threshold for predicting postoperative complications, the sensitivity and specificity rates were 81.4% and 79. 5% , respectively. Conclusion CPRI is one of the important factors to predict postoperative complications after lung cancer surgery. However, it can't predict all complications and should be considered together with other factors.