摘要
目的研究太空诱变机理。方法利用染色体DNA随机扩增多态性分析 (RAPD)技术 ,对经“神舟”3号返回式飞船搭载的高产红曲霉菌进行DNA多态性分析。结果突变株基因组DNA发生了改变。结论突变株洛伐他汀产量的提高与其遗传基因的变异有关 。
Objective To study the mechanism of microbial mutation in aerospace. Method Random Amplified Polymorphic DNA (RAPD) was used to analyze the polymorphism of high Lovastatin-producing mutants. Result Variations occurred in genomes of these mutants. Conclusion The high Lovastatin producibility of the mutants is due to the variation of genomes, therefore the microbial mutation in the aerospace is achieved via the variation of hereditary genes in the microbes.
出处
《航天医学与医学工程》
CAS
CSCD
北大核心
2004年第5期374-376,共3页
Space Medicine & Medical Engineering
基金
军转民技术开发项目资助 (科工民 [2 0 0 2 ] 2 98)
关键词
空间环境
搭载
红曲霉菌
基因突变
突变株
space environments
carry
monascus purpureus
gene mutation
mutants
