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HBV前-C区突变研究进展 被引量:7

Progress of Study on HBV Mutant in Precore Region
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摘要 许多慢性乙型肝炎患者感染的乙型肝炎病毒(HBV)是前-C区突变株,虽然这些患者血清中抗-HBe阳性,但体内病毒仍然在持续地复制。HBV前-C区突变经常发生在nt1896、1858和1899。如果感染的是HBV前-C区突变株,则可能导致HBeAg阴性患者的病情加重。拉米夫定、干扰素以及其他一些因素可以诱导HBV前-C区突变的发生。
出处 《国外医学(流行病学.传染病学分册)》 2004年第4期223-225,230,共4页 Epidemiology Lemology Foreign Medical Sciences
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