416例血象有异淋者抗HCMV-IgM及抗EBV-IgM的检测

Examination of Anti-HCMV-IgM and Anti-EBV-IgM in 416 Cases with Hetero-lymphocyte in Hemogram

目的 探讨血象中异型淋巴细胞所占百分比及形态的改变与HCMV、EBV感染的关系。方法 选择经 3次涂片镜检及过氧化酶染色确诊有异型淋巴细胞的患者 4 16例 ,采用ELISA法进行抗HCMV -ⅠgM及抗EBV -ⅠgM的血清学检测。结果 血象异型淋巴细胞所占百分比及形态种类分别与抗EBV -ⅠgM阳性例数比较 (χ2 分别为 133 4 1、130 4 1,P均小于 0 0 1) ,有显著性差异并随异型淋巴细胞百分比及形态种类的增加 ,抗EBV -ⅠgM阳性率在明显增加 ,而抗HCMV -ⅠgM阳性率却略有下降趋势 ,但不明显。结论 血象中异型淋巴细胞所占百分比及形态种类与EBV感染密切相关 ,与HCMV感染关系不大。

Objective To investigate the relationship between the percentage and shape types of the hetero-lymphocyte in hemogram and the infection of HCMV and EBV. Methods By three smear microscopy and peroxide staining. 416patients with hetero-Iymphocyte in hemogram were chosen for the serological examination of anti-EBV-ⅠgM and anti-HCMV-IgM with ELISA. Result Compare the percentage and shape kinds of the hetero-Iymphocyte with the quantity of cases of positive anti-EBV-ⅠgM, there were significantly difference (χ 2=133.41,130.31,P<0.01), and when the percentage and shape kinds increased, the positive rate of anti-EBV-ⅠgM had the tendency of increase apparently, as to the anti-HCMV-IgM, it declined slightly but not apparent. Conclusion The percentage and shape kinds of hetero-Iymphocyte in hemogram maybe involved in the infection of EBV, but there was no significant influence on the infection of HCMV.