3Leischner M,Holtmeier J,Achermann H,et al.The influence of sulinac on patients with primary biliary cirrhosis that responds inconmpletely to ursodeoxycholic acid:a pilot study[J].Eur J Gastrenterol Hepatol,2002,14(12):1369
4Gunsar F,Skarca US,Ersoz G,et al.Clinical and biochemical features and therapy respons in primary biliary cirrhosis and primary biliary cirrhosis-autoimmune hepatitis overlap syndrome[J].Hepatogastroenterology,2002,49(47):1195
5Angelico M,Gandin C,Pescarmona E et al.Recombinant interferon-alpha and ursodeoxycholic acid versus interferon-alpha alone in the treatment of chronic hepatitis C:a randomized clinical trial with long -term follow-up[J].Am J Gastroenterol,1995,90(2):263
6Rodrigues CMP,Fan G,Ma X,et al.A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation[J].J Clin Invest,1998,101(12):2790
7Beuers U,Boyer JL,Paumgartner G.Ursodeoxycholic acid in cholestasis: potential mechanisms of action and thepapeitic applications[J].Hepatology,1998,28(6):1449
8Kowdley KV.Ursodeoxycholic acid therapy in the hepatobiliary disease[J].Am J Med,2000,108(6):481
9Papatheodoridis GV,Hadziyannis ES,Deutsch M,et al.Ursodeoxycholic acid for primary biliary cirrhosis:final results of a 12-year,prospective,randomized,controlled trial[J].Am J Gastroenterol,2002,97(8):2063
10Ursodeoxycholic acid:a second look.Primary biliary cirrhosis:dashed hopes[J].Prescrire Int,2002,11(59):67