2型糖尿病的大动脉疾病

Aorta Disease of Type 2 Diabetes

目的:观察2型糖尿病患者的大动脉病变情况。方法:对302例2型糖尿病患者(糖尿病组)和180例无糖尿病的健康体检者(对照组)行血管超声检查,观察颈总动脉、颈动脉窦、股动脉和肱动脉舒张期内膜之中层厚度,同时分析临床大动脉病变情况。结果:①糖尿病组中186例(61.6％)出现至少一个部位的大动脉壁厚度异常,而对照组仅有24例(13.3％);②糖尿病合并大动脉壁厚度异常的患者中有134例(72％)为两处或两处以上病变,而对照组中仅有3例(12.5％)为两处病变;③糖尿病组有脑卒中病史19例、心肌梗死病史10例和下肢坏疽4例,而对照组有脑卒中病史3例和心肌梗死病史2例。结论:大动脉病变为2型糖尿病患者较常见并发症,并多累及不同部位。

Objective: To observe aorta lesion in type 2 diabetes patients. Methods: 320 type 2 diabetes patients (diabetes group) and 180 healthy peoples without diabetes (placebo group) were measured with Doppler ultrasound to observe the intima - medial thickness of common carotid artery, carotid sinus, femoral artery and brachial artery during diastole, and to analysis clinical aorta lesion. Results: (1) 186 cases (61.6 %) of diabetes group appeared at least one site of abnormal thickness of aorta wall, versus there were only 24 cases (13.3 %) in placebo group. (2) 134cases (72%) of diabetes patients with abnormal thickness of aorta wall appeared two or above sites of lesions, versus there were only 3 cases (12.5 %) appeared two sites of lesions in placebo group. (3) There were 19 cases of stroke history, 10 cases of myocardial infarction history and 4 cases of gangrene history of lower limb in diabetes group, versus there were only 3 cases of stroke history and 2 cases of myocardial infarction history in placebo group. Conclusion: Aorta lesion is a common complication of type 2 diabetes patients. It mostly damages different sites of aorta.