腮腺造影唇腺活检对Sjgren综合征的诊断价值

Evaluation of Parotid Sialography and Labial Salivary Gland Biopsy to the Diagnosis of Sj■gren Syndrome

对100例综合征患者进行腮腺造影及唇腺活检、组织病理学检查，87例患者显示腮腺末梢导管扩张性改变；90例显示局灶性淋巴细胞浸润，符合郑麟蕃氏Ⅱ级，59例符合Chisholm4级。结果提示了疾病中两种腺体损害的一致性，也证实了损害的不均衡性。本研究提示了一种联合观察腮腺造影和唇腺活检结果诊断涎腺损害的新方法。

To investigate the relationship between the change of parotid sialograms and the results of labial gland biopsies in the patients with Sj6gren syndrome (SS). Methods Parotid sialography and labial salivary gland biopsy were performed on 100 patients with Sjgren syndrome. Results The sialectasis of parotid terminal ducts was found in 87 patients, the widening only of main ducts was found in 8 patients, and 5 cases showed normal sialograms. The results of labial sa1ivary gland biopsies showed, that 90 cases had focal lymphocytic sialadenitis (Zhen Linfan's grade score of 2), 59 cases had a score of 4 accoding to Chisholm's grading score; moderate scattered lymphocitic infiltration was shown in 10 patients. Conclusion Our results suggested that the lesions of parotid gland and labial salivary gland in SS were concerted closely. Therefore a new way of combining the changes of parotid gland and labial salivary gland for the diagnose of SS was proposed.