健康体检者2456名脉压、收缩压和舒张压与代谢综合征的关系

Relationship of pulse pressure,systolic pressure and diastolic pressure with metabolic syndrome in 2 456 healthy people

目的:探讨脉压、收缩压、舒张压和代谢综合征的关系。方法:对2456名健康体检者的脉压、收缩压、舒张压和代谢综合征进行观察。结果:在各年龄组代谢综合征患者(n=309)脉压明显升高犤40～54岁组、55～69岁组和≥70岁组分别为(49±11),(54±11)和(59±13)mmHg,1mmHg=0.133kPa犦,与对照组(n=2147)比较,差异有显著性意义(t=3.54,5.15,2.22;P<0.05～0.01);40～70岁代谢综合征组患者收缩压犤40～54岁组和55～69岁组分别为(135±17)和(139±15)mmHg犦和舒张压犤40～54岁组和55～69岁组分别为(86±9)和(85±10)mmHg犦明显升高,与对照组比较,差异有显著性意义(t=4.19,5.21,8.81,2.20;P<0.05～0.01),在年龄大于70岁时升高不明显(P>0.05)。结论:代谢综合征患者脉压、收缩压和舒张压明显升高,脉压升高,可能参与代谢综合征对心、脑血管疾病的损伤。

AIM:To study the relationship between pulse pressure,systolic pressure,diastolic pressure and metabolic syndrome. METHODS:Pulse pressure,systolic pressure,diastolic pressure and metabolic syndrome in 2 456 healthy people were observed. RESULTS:Pulse pressure of patients with metabolic syndrome(n=309) was significantly increased in all age groups,which was(49±11),(54±11) and(59±13) mm Hg(1 mm Hg=0.133 kPa) in age 40 to 54,55 to 69 and over 70(including 70) group,respectively.It was significantly different from control group(n=2 147)(t=3.54,5.15,2.22;P< 0.05 to 0.01). Systolic pressure[aged 40 to 54:(135±17) mm Hg;aged 55 to 69:(139±15) mm Hg] and diastolic pressure[aged 40 to 54:(86±9) mm Hg;aged 55 to 69:(85±10) mm Hg] of patients with metabolic syndrome were obviously increased in the age of 40 to 70 years old,which was significant difference compared with control group(t=4.19,5.21,8.81,2.20;P< 0.05 to 0.01).But patients with metabolic syndrome in the age over 70 years old were not significantly increased(P >0.05). CONCLUSION:The pulse pressure,systolic pressure and diastolic pressure are significantly increased in patients with metabolic syndrome,which take part in the injury of cardiovascular and cerebrovascular diseases caused by metabolic syndrome.