慢性阻塞性肺疾病患者的睡眠质量调查

Survey of sleeping quality in patients with chronic obstructive pulmonary disease

目的:进行慢性阻塞性肺疾病(chronicobstructivepulmonarydisease,COPD)患者睡眠质量的调查,研究其规律性。方法:研究对象为2000-08/2003-08在本院门诊就诊和住院治疗的55例COPD患者。病例纳入标准:①符合1997年中华医学会制定的COPD诊疗规范中有关COPD稳定期诊断标准。②自愿接受各种量表调查。排除患有其他严重的躯体性疾病;有精神疾病或精神疾病家族史;有严重智力或认知障碍患者。分别接受了睡眠质量调查和血气检查,并与对照组同期结果进行比较。结果:在睡眠质量比较中,COPD组的入睡(1.18±0.29)、睡眠维持(0.41±0.05)、睡眠自评(0.79±0.11)、午休时间(1.35±0.20)、睡眠总时间(1.02±0.24)、梦记忆情况(1.16±0.14)等因子评分和睡眠质量总分(5.16±0.88)均明显高于对照组(t=2.201～3.137,P<0.01～0.05)。COPD患者按血氧分压水平分组后,血氧分压水平明显偏低组(21例)的入睡、睡眠维持、睡眠自评、睡眠总时间、梦记忆情况等因子评分和睡眠质量总分均明显高于血氧分压水平偏低组(34例)(t=2.092～3.108,P<0.01～0.05)。结论:COPD患者有明显的睡眠质量下降,与血氧分压水平有一定联系。

AIM:To study the sleeping quality of patients with chronic obstructive pulmonary disease(COPD) and explore its regularity. METHODS:Totally 50 COPD patients treated in the out patient clinic and inpatient department from August 2000 to August 2003 were selected. Inclusive criteria:①In accordance with diagnosis criteria on COPD stationary phase made by China Medical Association(CMA) in 1997;②Patients accepted various investigations by scales,excluding certain serious body diseases,psychosis or psychosis family history,serious intelligent or cognitive handicap.Patients received sleeping quality investigation and sap examination,and the results were compared with those in the control group simultaneously. RESULTS:In the comparison of sleeping quality scores of factors like falling asleep(1.18±0.29),sleeping maintenance(0.41±0.05),sleeping self rating(0.79±0.11),noontime rest(1.35±0.20),total sleeping time (1.02±0.24),dreaming memory(1.16±0.14), etc.and total score of sleeping quality(5.16±0.88) in the COPD group were obviously higher than those in the control group(t=2.201 to 3.137, P< 0.01 to 0.05).After COPD patients were divided on the basis of blood partial pressure of oxygen, scores of factors like falling asleep,sleeping maintenance, sleeping self rating, total sleeping time and dreaming memory,and total score of sleeping quality were significantly lower in patients with the lower level of blood partial pressure of oxygen(n=21) than those with the higher level of blood partial pressure of oxygen(n=34)(t=2.092-3.108, P< 0.01-0.05). CONCLUSION:Sleeping quality of COPD patients decreases obviously, which is related to the level of blood partial pressure of oxygen.