摘要
目的 了解江苏省 2 0 0 1~ 2 0 0 3年伤寒、副伤寒菌株的耐药情况及伤寒菌株的噬菌体分型情况 ,掌握伤寒、副伤寒的流行规律 ,为今后的防制工作提供科学依据。方法 对江苏省2 0 0 1~ 2 0 0 3年收集的 1 81株伤寒、副伤寒进行耐药性监测 ,对其中的 1 36株伤寒菌株进行噬菌体分型。结果 江苏省 2 0 0 1~ 2 0 0 3年 1 36株伤寒菌株可分为 1 4个型 ,分型率 73.2 1 % ,主要噬菌体菌型为J1、M 1和D2 ,分别占可分型菌总数的 1 4 .2 9%、1 3.39%和 1 0 .71 %。不同年份、不同地区伤寒菌株的分型率不同 ,2 0 0 2和 2 0 0 3年以里下河地区的分型率相对较高。伤寒、副伤寒菌株均对磺胺、红霉素、复方新诺明和氨苄青霉素具有不同程度的耐药性 ,副伤寒菌株的耐药谱较伤寒菌株宽。结论 伤寒噬菌体分型结果显示 。
Objective To explore the situation of drug resistance of S. typhoid and S. paratyphoid strains and bacteriophage type of S. typhoid form 2001 to 2003 in Jiangsu Province, to master the epidemiological rules, and to provide scientific evidences for the future prevention and control. Methods Drug resistance surveillance was executed on the 181 strains of S. typhoid and S. paratyphoid collected from 2001 to 2003, and 136 S. typhoid strains of them were identified using 96 type Vi Ⅱ bacteriophage. Results 14 types were found and typing rate was 73.21%. J1, M1 and D2 were the three main phagotypes and typing rates were 14.29%, 13.39%, and 1071% respectively. The typing rate was different according to the year and areas, and it was relatively higher in 2002 and 2003 and in area of the Lixiahe valley. All 181 strains of S. typhoid and S. paratyphoid were resistant to SD, and some of them were resistant to ETM, COS and AMP. The spectrum of S. paratyphoid was broader than S. typhoid. Conclusions The study illustrated that the main phage type has no obvious change in Jiangsu province.
出处
《疾病控制杂志》
2004年第5期402-404,共3页
Chinese Journal of Disease Control and Prevention