甘肃省武威市胃癌发病特征研究

Study of the characteristics of gastric carcinoma in Wuwei City of Gansu province

目的 研究武威市胃癌的发病特征及发病趋势。方法 应用回顾调查的方法对当地医院2 3年间接受胃镜检查的 85 42 7份病例中检出的 743 6例胃癌患者的病例资料进行研究。结果 胃癌胃镜检出率为 8.7%。男∶女 =2 .78∶1.0 0 ,40～ 70岁为胃癌的高发年龄 ,占总数的 92 .0 %。胃癌患者的幽门螺杆菌 (Hp)感染率为 64 .6% ,高于胃癌低发区及平均Hp感染水平 ;分化差的胃癌高于分化好者。贲门胃底癌最多见 ,占胃癌总数的 43 .8% ,低分化腺癌为最常见病理类型。结论 武威市胃癌的发病与Hp感染有关 ;2 0余年来胃癌发病部位由远侧向近侧迁移 ,胃癌的部位越高 ,其恶性度越高。

Objective To study the pathological features and developmental tendency of gastric carcinoma(GC) in Wuwei City. Methods The clinical data of 7346 cases of GC found in 85427 cases undergoing endoscopy in Wuwei City from 1977 to 2000 were retrospectively analysed. Results The detectation rate of GC by endoscopy in Wuwei City was 8.7%. GC developed to a peak at 40～70 years of age(92.0%).In the GC cases, the Hp infection rate was 64.6%, which is higher than that in the area of low incidence of GC and the general population. Hp infection rate in poorly differentiated adenocarcinoma was higher than that in well differenciated type.Most GC(43.8%) were located in the proximal portion of the stomach. Poorly differentiated adenocarcinoma appeared to be the most common pathological type. Conclusions GC in Wuwei City is related to Hp infection. GC location has shifted from the distal to the proximal portion of the stomach in the last 23 years.