全反式维甲酸、α-干扰素联合小剂量阿糖胞苷治疗低增生性急性髓性白血病疗效观察

ATRA、α-INF and Small dose Cytarabine to Treat 8 Cases of Acute low Hyperplastic Marrow Leukemia

目的 :探讨应用全反式维甲酸、α 干扰素联合小剂量阿糖胞苷方案治疗低增生性急性髓性白血病的作用和机制。方法 :对 1995年至 2 0 0 4年期间收治低增生性急性髓性白血病 8例应用上述方案治疗并评价疗效。结果 :所有病例均获达到完全缓解 ,平均治疗时间 35d ,毒副作用较小。结论 :全反式维甲酸、α 干扰素联合小剂量阿糖胞苷方案治疗低增生性急性髓性白血病缓解率较高 ,平均治疗时间短 ,缓解期较长 ,毒副作用相对较少。

Objective To discuss the effect of ATRA、α-INF and small dose Cytarabine to treat 8 cases of acute low hyperplastic marrow leukemia and its function.Methods To treat 8 cases of the disease with ATRA、α-INF and small dose Cytarabine.Results All the cases get fully released and the average treating time is 35 days with less bad effect.Conclusion ATRA、α-INF and small dose cytarabine to treat the cases of acute low hyperplastic marrow leukemia proves to be effctive with shorter treating time , longer releasing time and less bad effect.