μ_3-S盖帽的外消旋金属簇合物的直接手性拆分

Direct Chiral Separation of (μ_3-S)-Bridged Racemic Metal Clusters

在自制的涂敷型纤维素 三(3,5 二甲基苯基氨基甲酸酯)手性固定相上直接拆分了μ3 S盖帽的外消旋四面体金属簇合物.同时考察了温度、流动相中的极性改性剂的种类及结构对手性拆分的影响.结果发现,在相同的色谱条件下,被拆分簇合物在异丙醇作改性剂的流动相中的拆分效果较好.

The direct chiral separation of (μ_3-S)-bridged racemic metal clusters was performed on cellulose-tris(3,5-dimethylphenylcarbamate) chiral stationary phase(CDMPC-CSP). In normal phase condition, the influence of temperature and mobile phase modifier on the chiral separation and retention were investigated. The results suggest that the structure and concentration of alcohol in the mobile phase have a pronounced effect on enantiomeric separation and retention.