磁场作用对小鼠学习记忆的影响

Effect of Magnetic Field on Learning and Memory in Mice

目的 :探讨磁场作用对小鼠学习记忆能力的影响。方法 :应用水迷宫学习模型测定并对比 30分钟磁场处理组、1 5分钟磁场处理组和非磁场处理的正常对照组动物的空间学习记忆能力。结果 :水迷宫学习训练的实验表明 30分钟磁场处理组与正常对照组比较 ,动物到达水下平台的时间延长 ;游程增加 ;平均游速减慢 ,且均具有显著性差异 (p <0 .0 5)。 1 5分钟磁场处理组与正常对照组比较 ,动物到达水下平台的时间延长 ,且具有显著性差异 (p <0 .0 5) ;游程和平均速度与正常对照组相比无显著性差异 (p >0 .0 5)。结论 :磁场处理 30分钟或 1 5分钟损伤小鼠的空间学习记忆能力 ,且以

Objective: To discuss the effects of magnetic field on learning and memory in mice. Methods: Kun-ming mice were divided into three groups:30 min. exposure of magnetic field group, 15 min. exposure of magnetic field group and control group. The changes of learning and memory behavior of mice were respectively observed with water maze after 15 min. or 30 min. exposure of magnetic field per day standing for 30 days. Results: Compared with control group, 15 min. or 30 min. exposure of magnetic field group mice took much time to acquire task in water maze(p<0.05). Conclusion: 15 min. or 30 min. exposure of magnetic field per day standing for 30 days can reduce learning and memory capability.