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2型糖尿病并发急性脑梗死患者血同型半胱氨酸测定的意义

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摘要 目的了解2型糖尿病(T2DM)并发急性脑梗死患者血浆同型半胱氨酸(Hcy)水平,进一步探讨糖尿病并发大血管病变的危险因素。方法应用快速微柱高压液相色谱法检测56例T2DM及47例DM并发急性脑梗死患者血浆Hcy,34例正常健康者为对照组,并测定有关生化参数,分析Hcy水平与急性脑梗死及Hcy与其他参数之间的关系。结果T2DM组及DM并发脑梗死组血浆Hcy明显高于对照组,P均<0.01,且DM并发脑梗死组高于DM无脑梗死组(P<0.01)。相关分析显示,血浆Hcy与年龄、DM病程、纤维蛋白原(Fg)、糖化血红蛋白(HbA1c)呈正相关,P<0.01。结论高Hcy血症与T2DM及DM并发急性梗死有密切相关。
机构地区 江西省人民医院
出处 《实用中西医结合临床》 2004年第5期13-14,共2页 Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
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