脂质体——基因载体

Liposomes for Gene Delivery

概述了基因载体的作用、类型和脂质体用于基因载体的发展历史,介绍了一类很有前途的基因载体-阳离子脂质体的组成结构和分类及其转基因的作用原理,讨论了影响阳离子脂质体/DNA复合物物理化学性质的参数及其目标复合物的制备方法.

The functions, the types and the history of liposomes for gene delivery are studied. The composition, the classification and the working principles of the transgenosis of the cationic liposome, which is a promising kind of gene delivery, are introduced. The parameters which affect the physical chemistry of cationic liposomes/DNA complexes and their preparation are discussed.