手性方酸衍生物的合成及在前手性酮的不对称催化还原反应中的应用研究进展

Chiral squaric acid derivatives:synthesis and application to catalytic asymmetric reduction of prochiral ketones

本文评述手性方酸衍生物的研究进展,包括多个系列的新型手性方酰化氨基醇及氨基酸配体的设计合成以及它们在前手性单酮和二酮的不对称催化还原反应中的应用。

This article reviews the development on studies of chiral squaric acid derivatives,including the design and synthesis of novel squaramidoalcohols and squaramidoacids,and their applications in catalytic asymmetric reduction of prochiral ketones and diketones.