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报告基因核医学显像及研究进展 被引量：1

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摘要 分子生物学及影像技术的发展,促使人类基因治疗试验能更好地开展.基因治疗其中一个主要问题是使治疗基因能有所受控地、有效地转染到靶组织,避免在非靶组织中表达.因此,在基因治疗过程中有必要对治疗基因进行监测.
作者 修雁 陈绍亮
机构地区 复旦大学附属中山医院核医学科
出处 《中华核医学杂志》 CAS CSCD 北大核心 2003年第6期374-376,共3页 Chinese Journal of Nuclear Medicine
关键词 报告基因 治疗基因 核医学显像 双功能基因显像 二步转录放大系统 基因表达断层显像
分类号 R817 [医药卫生—影像医学与核医学]
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参考文献28

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同被引文献25

  • 1何苗,祁春梅,武维恒,侯先存,李尧梅,周鹏,李莉.骨髓间质干细胞治疗家猪急性心肌梗死的SPECT显像[J].中华核医学杂志,2006,26(3):165-167. 被引量：3
  • 2Lunde K, Solheim S, Aakhus S, et al. Intracoronary injection of mononuclear bone marrow ceils in acute myocardial infarction. N Engl J Med, 2006, 355: 1199-1209.
  • 3Beeres SLMA, Bax JJ, Dibbets P, et al. Effect of intramyocardial injection of autologous bone marrow-derived mononuclear ceils on perfusion, function, and viability in patients with drug-refractory chronic ischemia. J Nucl Med, 2006, 47: 574-580.
  • 4Erbs S, Linke A, Adams V, et al. Transplantation of blood-derived progenitor cells after recanalization of chronic coronary artery occlusion: first randomized and placebo-controlled study. Circ Res, 2005, 97 : 756-762.
  • 5Kang H J, Kim HS, Zhang SY, et al. Effects of intracoronary infusion of peripheral blood stem-cells mobilised with granulocyte-colony stimulating factor on left ventricular systolic function and restenosis after coronary stenting in myocardial infarction: the MAGIC cell randomised clinical trial. Lancet, 2004, 363: 751-756.
  • 6Strauer BE, Brehm M, Zeus T, et al. Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans. Circulation, 2002, 106: 1913-1918.
  • 7Bartunek J, Vanderheyden M, Vandekerckhove B, et al. Intracoronary injection of CD133-positive enriched bone marrow progenitor cells promotes cardiac recovery after recent myocardial infarction: feasibility and safety. Circulation, 2005, 112: Ⅰ 178- Ⅰ 183.
  • 8Janssens S, Dubois C, Bogaert J, et al. Autologous bone marrow derived stem-cell transfer in patients with ST-segment elevation myocardial infarction: double-blind, randomised controlled trial. Lancet, 2006, 367: 113-121.
  • 9Perin EC, Dohmann HF, Borojevie R, et al. Improved exercise capacity and ischemia 6 and 12 months after transendocardial injection of autologous bone marrow mononuclear cells for ischemic cardiomyopathy. Circulation, 2004, 110: Ⅱ213-Ⅱ218.
  • 10Kaminek M, Meluz, in J, Panovsky R, et al, Individual differences in the effectiveness of intracoronary bone marrow cell transplantation assessed by gated sestamibi SPECT/FDG PET imaging. J Nucl Cardiol, 2008, 15 : 392-399.

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中华核医学杂志
2003年 第6期

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