壶腹部癌的临床病理分析(附41例报告)

CLINICAL AND PATHOLOGICAL ANALYSIS OF AMPULLA CANCER (41 CASES REPORTS)

目的 探讨壶腹部癌的临床病理特点 ,提高对壶腹部癌的临床诊治水平。方法 回顾性分析 4 1例经手术及病理确诊为壶腹部癌患者的临床病理资料 ,寻找其特点及联系。结果 4 1例壶腹部癌以梗阻性黄疸和上腹部不适、疼痛为突出的临床表现 ;影像学检查主要表现为壶腹部肿物及胆、胰管扩张、狭窄、中断 ;内镜对十二指肠乳头及附近粘膜病变发现率高 ,活检阳性达 83% ;病理上以腺癌多见 ,呈浸润性生长 ,易侵犯胰头和十二指肠。 结论 上腹部不适、疼痛是壶腹部癌的早期症状 ,对早期诊断有重要的提示作用 ;超声及内镜 。

Objective To investigate the clinical and pathological characteristics of ampulla cancer,and to improve the clinical diagnosis and treatment.Methods The data from 41 cases with ampulla cancer which had been diagnosed by operation and pathology,were analysised statistically.Result The main clinical symptons were obstructive jaundice,epigastric discomfort and pain.The main imagic characteristics were ampullary masses,dilations,constrictions,breaks of biliary and pancreatic duct.The sensitivity of endoscopy for patilla of duodenum and mucosa lesion was higher,about 83 percent of ampulla carcer could be diagnosed by biopsy.with pathology,adenocarcinoma was the main pattern for ampulla carcer,and encroached easily on the head of pancreas and duodenum by infiltrated growth.Conclusions Epigastric discomfort and pain are clinical symptons in early period,and it has an important role for early diagnosis.Ultrasonography and endoscopy ,especially endoscopy hiopsy,have important functions for the detection and diagnosis of ampulla carcer.