结节病15例临床分析

Clinical analysis of15cases of pulmonary sarcoidosis

目的总结结节病的临床特征,提高临床医生对本病的认识和诊治水平。方法对15例结节病患者的临床资料进行回顾性分析。结果15例结节病患者,以呼吸系统症状为首发表现者7例,以肺外表现为首发症状者6例,无症状者2例。X线及胸CT提示双肺门及纵隔对称性淋巴结肿大者13例,12例患者血管紧张素转化酶升高,血沉加快者10例,结核纯蛋白衍化物试验仅1例阳性。结论肺结节病多见于中青年成人,临床症状不典型,在诊断上应综合其临床表现、胸部X片、CT及实验室检查结果。

Objective To fa ci litate the diagnosis and treatment of pulmonary sarcoidosis. Methods The clinica l data of 15 cases of pulmonary sarcoidosis were retrospectively analyzed. Resu lts Among these patients, 7 were identified with respiratory symptoms as the in itial clinical representations, and 6 patients initially presented extrapulmonar y symptoms, with 2 patients having no discomfort. Chest X-ray and lung CT scan results of 13 cases showed symmetrical lymph node enlargement in the bilateral lung hilus and mediastinum. Twelve patients had increased serum angiotensin-conv erting enzyme levels, and 10 had increased erythrocyte sedimentation rate, with only 1 case showing positive result in purified protein derivative skin test. Conclusion Pulmonary sarcoidosis has atypical clinical symptoms, and the diagnos is should be reached by a careful evaluation of the clinical representations in conjunction with X-ray, CT, and laboratory test results.