力竭运动后大鼠骨骼肌不同肌纤维线粒体钙含量和肌浆网Ca^(2+)-ATP酶活性变化

Changes of Ca^(2+)in mitochondria and Ca^(2+)-ATP_(ase) activity in sarcoplasmic reticulum(SR) of different skeletal muscle fiber types in rat after exhaustive exercise

为探讨急性力竭运动后大鼠骨骼肌不同肌纤维内Ca2 + 转运功能变化 ,测定了股四头肌红肌和白肌线粒体钙含量和肌浆网Ca2 + ATP酶活性 ,结果红肌和白肌线粒体Ca2 + 含量增加 ,肌浆网Ca2 + ATP酶活性降低 ,说明急性力竭运动后肌细胞内Ca2 + 转动功能发生了改变 ,影响了肌肉收缩特性 。

In order to observe changes of Ca 2+ transport in different skeletal muscle types in rat after exhaustive exercise,Ca 2+ content in mitochondria and (SR)Ca 2+ ATP ase activity in SR were determined,The results showed that mitochondria Ca 2+ increased and (SR)Ca 2+ ATP ase activity decreased.This indicated that cellular calcium transport function was changed.This change may be one of the important factors causing the decrease of muscular contractive function after exhaustive exercise and might be closely related to exercise induced skeletal muscle fatigue.