高分子基质作用下草酸钙的仿生合成

STUDY ON BIONICS SYNTHESIS OF CALCIUM OXALATE INDUCED BY MACROMOLECULE

依据生物矿化基本原理,利用硫酸软骨素(CS)作为调控基质,在动态环境下诱导草酸钙凝集结晶,并用原子力显微镜(AFM)和XRD研究其在高分子体系中聚集生长的过程及机制。实验结果显示在高分子基质调控下,草酸钙聚集成由六个正三角形组成的薄状六边形晶体,其精细结构体现为球晶的紧密堆积,并存在局部生长缺陷。结晶过程主要受成核机制控制,也受缺陷机制的影响。其本质是高分子官能团与Ca2+之间存在着静电匹配作用和高分子基质与晶体空间构型互补的结果。

Chondroitin sulfate(CS) was used as manipulative fundus to induce the aggregation and crystal of calcium oxalate under the dynamic condition. The process and mechanism of calcium oxalate growth were studied by atomic force microscope(AFM) and XRD. It is found that calcium oxalate is assembled to hexagon flaky crystal which is made up of six positive triangles, and its subtle structure is really the compact pile of spherical crystals. At the same time, local lacuna exists in the crystal. The process of crystal formation is mainly controlled by nucleation mechanism and also affected by lacuna mechanism.