直肠癌细胞DNA含量流式细胞仪分析

Analysis of DNA Content from Cells of Rectal Cancer with Flow Cytometry

我们应用流式细胞仪分析了62例石蜡包埋直肠癌切片的DNA含量。探讨了与病理学及临床预后的关系。结果显示,62例中有二倍体肿瘤34例,占54.8%;非二倍体肿瘤有28例,占45.2%。二倍体肿瘤病人5年生存率为79.4%;非二倍体肿瘤病人5年生存率为23.7%。DNA含量与肿瘤的预后密切相关,为直肠癌的临床预后的判定提供了新的重要指标。

DNA contents in the paraffin embedded sections from 62 patients with rectal cancer were analysed with flow cytometry. The results showed that surviral rate of 5 years was 79.4% in 34 cases with diploid tumors and 28.7% in 28 cases with aneuploid tumors. The DNA content is closely relative to the prognosis and it can be an important index of evaluating prognosis of rectal cancer.