小儿原发肾病综合征血流变学观察及对肾病的影响

Hemorheology and Its Affection in Children with Primary Nephrotic Syndrome

我们观察了17例小儿原发肾病综合征病人的血流变学,并与13例正常人做对照。各项指标均有增高。对其中9例应用激素治疗4周以上蛋白尿仍大于“++”的病人,用肝素改变血流变学。结果3例病人尿蛋白明显减少,全部病人用药3日左右有明显利尿作用。这表明改善血流变学异常是提高肾病缓解率的重要环节之一。

We observed hemorheology of 17 children with primary nephrotic syndrome and compared the results with 13 normal cases. The index observed are higher. 9 cases among them given by hormone for 4 weeks, which urinary protein kept more than '++', were treated with heparin. The results showed that urinary protein decreased obviously in 3 cases. The manifest diureses appeared in all the patients after using heparin for 3 days.