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轮状病毒我国地方株NSP4基因与病毒毒力关系的探讨

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摘要 轮状病毒是引起严重婴幼儿腹泻的最重要的病毒病原[1],在发展中国家每年至少有60万病人死于轮状病毒感染造成的腹泻.轮状病毒属呼肠孤病毒科,双链RNA病毒,三层蛋白壳包绕核心的11个分节段双链RNA基因片段.外壳是VP4和VP7蛋白,内壳是VP6蛋白.VP6是主要的组、亚组特异性抗原,VP4和VP7分别是P血清型、G血清型及血清亚型的分型抗原.
出处 《医学研究通讯》 2004年第8期12-15,共4页 Bulletin of Medical Research
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