226例泌尿系感染病原菌分布及耐药性分析

Analysis of distribution and resistance to antibiotics of pathogens in 266 patients with genitourinary tract infections.

目的 监测海南省人民医院近几年泌尿系感染病原菌的分布及耐药性分析 ,指导临床合理应用抗生素。 方法 回顾性分析 2 0 0 1年 1月～ 2 0 0 3年 6月泌尿系感染患者病原菌分布及耐药性。 结果 大肠埃希菌仍是引发泌尿系感染的主要病原菌 ( 82株 ) ,占 3 6.3 % ,其次是真菌、肠球菌、铜绿假单胞菌、肺炎克雷伯菌等。细菌对各种抗生素耐药率增加 ,对青霉素类抗生素耐药率在 70 6%～ 10 0 0 %之间 ;对喹诺酮类抗生素耐药率在 5 2 9%～ 10 0 0 %之间 ;G-杆菌对亚胺培南较敏感 ,耐药率在 0 0 %～ 11 8%之间 ;G+ 球菌对万古霉素均敏感 ,耐药率为 0 0 %。 结论 临床医生必须关注本地区病原菌分布及耐药情况 ,合理应用抗生素 。

Objective To analyze the distribution and resistance of the pathogen, from 26 cases with urinary system infections, to antibiotics and guide clinical application of antibiotics. Methods Retrospective study was used to understand the distribution and resistance of pathogens, detected from 26 patients with urinary system infections in 2001～2003 to antibiotics. Results Escherichia. coli is the main pathogen responsible for urinary system infections (accounted for 82%) and followed by fungi, enterococci, P. aeruginosa and Klebsiella peumoniae, etc. The resistance of bacteria to antibiotics is increasing the resistance to penicillin is about 70.6%～100.0%,52.9%～100.0%, to quinolones. Gram negative bacilli is still sensitive to imipenem with a resistance rate of about 0.0%～11.8%, while the gram positive cocci is still sensitive to vancomycin. Conclusion More attention be paid to distribution and resistance of pathogens in the localities and antibiotics be used in a reasonable way to reduce the speread of resistance of the bacteria to antibiotics.